Yes it is possible:
1. Connect to m300p via USB-Cable (e.g. using a Notebook)
2. Rename the folder "Alpine" to "Alpine_save"
3. Create a folder "Alpine"
4. Copy the Destinator files into the folder "Alpine"
5. Rename Destinator.ext to AlpineNavi.exe
6. Restart n300p
Note:The n300p always starts automatically the file "\\Alpine\AlpineNavi.exe
(If anyone knows how to get a TomTom running on the n300p please let me know!!!)
Is there any other Navi-Software running on the M300P apart fom iGO8 and Destinator?