I know nothing about your specific devices, but I can suggest why your cursor disappears. When you load IGO, it will want to connect the com port to the GPS receiver, so unless you have 2 com ports, your mouse has just lost its connection to the application software. The usual solution to problems like this is to install a port splitter, which will allow you to share one virtual com port between two devices. Usually, this problem arises when there is contention for a single com port between the GPS receiver and the TMC receiver. Google GPS port splitter.